Anti-SPINT2 Polyclonal Antibody
Cat: K109014P
Summary:
| 【Product name】：Anti-SPINT2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：10653 | 【Swiss Prot】：O43291 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human SPINT2 | |
| 【Public Immunogen Range】：105-155/252aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Immunohistochemistry of paraffin-embedded Human endometrial cancer with SPINT2 antibody diluted at 1:80