Anti-PDK3 Polyclonal Antibody - SAlexa Fluor 488
Cat: K109019P - SAlexa Fluor 488
Summary:
| 【Product name】：Anti-PDK3 Polyclonal Antibody - SAlexa Fluor 488 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5165 | 【Swiss Prot】：Q15120 |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human PDK3 | |
| 【Public Immunogen Range】：1-407aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Inhibits pyruvate dehydrogenase activity by phosphorylation of the E1 subunit PDHA1, and thereby regulates glucose metabolism and aerobic respiration. Can also phosphorylate PDHA2. Decreases glucose utilization and increases fat metabolism in response to prolonged fasting, and as adaptation to a high-fat diet. Plays a role in glucose homeostasis and in maintaining normal blood glucose levels in function of nutrient levels and under starvation. Plays a role in the generation of reactive oxygen species.
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