Anti-RAB38 Polyclonal Antibody
Cat: K109026P
Summary:
| 【Product name】：Anti-RAB38 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：23682 | 【Swiss Prot】：P57729 |
| 【Tested applications】：IF,IHC,WB | |
| 【Recommended dilution】：WB 1:8000-12000. IHC 1:25-100. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human RAB38 | |
| 【Public Immunogen Range】：1-211aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
May be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1. Involved in peripheral melanosomal distribution of TYRP1 in melanocytes; the function, which probably is implicating vesicle-trafficking, includes cooperation with ANKRD27 and VAMP7. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays an important role in the control of melanin production and melanosome biogenesis. In concert with RAB32, regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes.
Verified picture:
Immunohistochemistry of paraffin-embedded Human liver cancer with RAB38 antibody diluted at 1:40
Western blot analysis with RAB38 antibody diluted at 1:10000;Lane: A431,Hela