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Anti-ATP6V1G1 Polyclonal Antibody
Cat: K109034P
Summary:
【Product name】:Anti-ATP6V1G1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:9550 【Swiss Prot】:O75348
【Tested applications】:IHC
【Recommended dilution】:IHC 1:50-200.
【Immunogen】:Recombinant protein of human ATP6V1G1
【Public Immunogen Range】:1-118aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe2+ prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation.
Verified picture:
Immunohistochemistry of paraffin-embedded Human testis cancer with ATP6V1G1 antibody diluted at 1:100