Anti-OTUB1 Polyclonal Antibody
Cat: K109081P
Summary:
| 【Product name】：Anti-OTUB1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：55611 | 【Swiss Prot】：Q96FW1 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-3000. | |
| 【Immunogen】：Recombinant protein of human OTUB1 | |
| 【Public Immunogen Range】：1-271aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
OTUB1 belongs to the ovarian tumor domain protease (OTU) subfamily of deubiquitinases, which could block ubiquitination leading to protein stability. OTUB1 mainly prefers k-48 and k-63 ubiquitin chains type, especially in k-48 ubiquitin chain. OTUB1 performs its deubiquitinating function via two distinct manners: the canonical and non-canonical manner. OTUB1 is involved in many critical immune response processes, containing CD8 T cell activation, PD-L1 related immune evasion, and several infectious diseases.
Verified picture:
Western blot analysis with OTUB1 antibody diluted at 1:2000;Lane:Hela,HepG2,HEK293,A375,HT29,293T,MCF7