Anti-CASP2 Polyclonal Antibody
Cat: K109091P
Summary:
| 【Product name】：Anti-CASP2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：835 | 【Swiss Prot】：P42575 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:25-100. | |
| 【Immunogen】：Recombinant protein of human CASP2 | |
| 【Public Immunogen Range】：153-431aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. Associates with PIDD1 and CRADD to form the PIDDosome, a complex that activates CASP2 and triggers apoptosis in response to genotoxic stress.
Verified picture:
Immunohistochemistry of paraffin-embedded Human breast cancer with CASP2 antibody diluted at 1:80