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Anti-Histone H2B Monoclonal Antibody
Cat: K200072M
Summary:
【Product name】:Anti-Histone H2B Monoclonal Antibody 【Source】:Mouse
【Isotype】:IgG1 【Purification】:Affinity purification
【Gene ID】:3018 【Swiss Prot】:P33778
【Tested applications】:WB,IHC
【Recommended dilution】:WB 1:2000-5000. IHC 1:100-300.
【Immunogen】:Synthetic Peptide
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Verified picture:
Immunohistochemistry of paraffin-embedded Human prostate cancer with Histone H2B antibody diluted at 1:200
Western blot analysis with Histone H2B antibody diluted at 1:3000;Lane:Hela