Anti-NR2C1 Polyclonal Antibody
Cat: K009735P
Summary:
| 【Product name】：Anti-NR2C1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：7181 | 【Swiss Prot】：P13056 |
| 【Tested applications】：ELISA,IHC,WB | |
| 【Recommended dilution】：WB 1:500-1000. IHC 1:20-1:200. | |
| 【Immunogen】：Recombinant protein of human NR2C1 | |
| 【Public Immunogen Range】：118-467aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Nuclear receptor subfamily 2 group C member 1 (NR2C1), also known as Orphan nuclear receptor TR2, is a member of the steroid/thyroid hormone receptor superfamily that controls a variety of processes, including growth, differentiation and development. TR2 is known to bind to regulatory elements of the erythropoietin gene, the muscle-specific aldolase A gene and the CNTF-15 gene. In addition to TR2, a related orphan receptor, designated TR4, has been identified. TR4 forms heterodimers with TR2, which are thought to be involved in neurogenesis and germ cell development. TR2 is known to be downregulated by both p53 and ionizing radiation, and it may play a role in linking p53 to members of the steroid recepr family.
Verified picture:
Immunohistochemistry of paraffin-embedded Human prostate cancer with NR2C11 antibody diluted at 1:100
Western blot analysis with NR2C1 antibody diluted at 1:500;Lane: SH-SY5Y cells.