Anti-CPT1A Polyclonal Antibody - Cy7
Cat: K109122P - Cy7
Summary:
| 【Product name】：Anti-CPT1A Polyclonal Antibody - Cy7 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1374 | 【Swiss Prot】：P50416 |
| 【Tested applications】：WB,IF,IHC,IP | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:100-300. IF 1:50-200. IP 1:200. | |
| 【Immunogen】：Recombinant protein of human CPT1A | |
| 【Public Immunogen Range】：1-340aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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