Anti-PAIP2 Polyclonal Antibody
Cat: K109150P
Summary:
| 【Product name】：Anti-PAIP2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：51247 | 【Swiss Prot】：Q9BPZ3 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:100-300. | |
| 【Immunogen】：Recombinant protein of human PAIP2 | |
| 【Public Immunogen Range】：1-127aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.
Verified picture:
Immunohistochemistry of paraffin-embedded Mouse berast cancer with PAIP2 antibody diluted at 1:200
Western blot analysis with PAIP2 antibody diluted at 1:2000;Lane: Mouse liver, Mouse kidney,Mouse brain,SH-SY5Y