Anti-APAF1 Polyclonal Antibody - Cy7
Cat: K109159P - Cy7
Summary:
| 【Product name】：Anti-APAF1 Polyclonal Antibody - Cy7 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：317 | 【Swiss Prot】：O14727 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human APAF1 | |
| 【Public Immunogen Range】：230-280/338aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis
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