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Anti-TINF2 Polyclonal Antibody - SAlexa Fluor 647
Cat: K109180P - SAlexa Fluor 647
Summary:
【Product name】:Anti-TINF2 Polyclonal Antibody - SAlexa Fluor 647 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:26277 【Swiss Prot】:Q9BSI4
【Tested applications】:FC ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:A synthetic peptide of human TINF2
【Public Immunogen Range】:395-445/451aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Isoform 1 may have additional role in tethering telomeres to the nuclear matrix.
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