Anti-DOK1 Polyclonal Antibody - SAlexa Fluor 555
Cat: K109181P - SAlexa Fluor 555
Summary:
| 【Product name】：Anti-DOK1 Polyclonal Antibody - SAlexa Fluor 555 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：1796 | 【Swiss Prot】：Q99704 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human DOK1 | |
| 【Public Immunogen Range】：325-375/481aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
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