Anti-UBR1 Polyclonal Antibody - SAlexa Fluor 640
Cat: K109222P - SAlexa Fluor 640
Summary:
| 【Product name】：Anti-UBR1 Polyclonal Antibody - SAlexa Fluor 640 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：197131 | 【Swiss Prot】：Q8IWV7 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:25-100. | |
| 【Immunogen】：A synthetic peptide of human UBR1 | |
| 【Public Immunogen Range】：1665-1715/1749aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. May be involved in pancreatic homeostasis. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth.
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