Anti-FRK Polyclonal Antibody - Biotin
Cat: K109239P - Biotin
Summary:
| 【Product name】：Anti-FRK Polyclonal Antibody - Biotin | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：2444 | 【Swiss Prot】：P42685 |
| 【Tested applications】：WB ELISA IHC ICC | |
| 【Recommended dilution】：WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human FRK | |
| 【Public Immunogen Range】：230-280/505aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor.
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