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Anti-UNC119 Polyclonal Antibody
Cat: K109261P
Summary:
【Product name】:Anti-UNC119 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:9094 【Swiss Prot】:Q13432
【Tested applications】:IHC
【Recommended dilution】:IHC 1:25-100.
【Immunogen】:A synthetic peptide of human UNC119
【Public Immunogen Range】:10-60/240aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Involved in synaptic functions in photoreceptor cells, the signal transduction in immune cells as a Src family kinase activator, endosome recycling, the uptake of bacteria and endocytosis, protein trafficking in sensory neurons and as lipid-binding chaperone with specificity for a diverse subset of myristoylated proteins. Specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Binds myristoylated GNAT1 and is required for G-protein localization and trafficking in sensory neurons. Probably plays a role in trafficking proteins in photoreceptor cells. Plays important roles in mediating Src family kinase signals for the completion of cytokinesis via RAB11A.
Verified picture:
Immunohistochemistry of paraffin-embedded Human liver cancer with UNC119 antibody diluted at 1:40