Anti-HSD17B8 Polyclonal Antibody
Cat: K109268P
Summary:
| 【Product name】：Anti-HSD17B8 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：7923 | 【Swiss Prot】：Q92506 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human HSD17B8 | |
| 【Public Immunogen Range】：1-261aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined.
Verified picture:
Immunohistochemistry of paraffin-embedded Human liver cancer using HSD17B8 antibody
diluted at 1:100
Western blot analysis with HSD17B8 antibody diluted at 1:2000;Lane: A549,HepG2,Human pancreatic cancer,Mouse liver