Anti-MEN1 Polyclonal Antibody
Cat: K109302P
Summary:
| 【Product name】：Anti-MEN1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：4221 | 【Swiss Prot】：O00255 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:2000-5000. IHC 1:25-100. | |
| 【Immunogen】：Recombinant protein of human MEN1 | |
| 【Public Immunogen Range】：226-575aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants.
Verified picture:
Immunohistochemistry of paraffin-embedded Human stomach cancer using MEN1 antibody diluted at 1:40
Western blot analysis with MEN1 antibody diluted at 1:4000;Lane: Jurkat,K-562,293T,A431,A549