Anti-CFLAR Polyclonal Antibody - SAlexa Fluor 555
Cat: K109397P - SAlexa Fluor 555
Summary:
| 【Product name】：Anti-CFLAR Polyclonal Antibody - SAlexa Fluor 555 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：8837 | 【Swiss Prot】：O15519 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human CFLAR | |
| 【Public Immunogen Range】：215-265/480aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity.
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