Anti-CLK1 Polyclonal Antibody
Cat: K109409P
Summary:
| 【Product name】：Anti-CLK1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：1195 | 【Swiss Prot】：P49759 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human CLK1 | |
| 【Public Immunogen Range】：280-330/484aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates: SRSF1, SRSF3 and PTPN1. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells and adenovirus E1A pre-mRNA.
Verified picture:
Immunohistochemistry of paraffin-embedded Human breast cancer with CLK1 antibody diluted at 1:100