Anti-GPR75 Polyclonal Antibody
Cat: K109420P
Summary:
| 【Product name】：Anti-GPR75 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：10936 | 【Swiss Prot】：O95800 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-3000. | |
| 【Immunogen】：A synthetic peptide of human GPR75 | |
| 【Public Immunogen Range】：260-310/540aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.
Verified picture:
Western blot analysis with GPR75 antibody diluted at 1:2000;Lane:HMC1,Hela,U937,K-562,A431