Anti-API5 Polyclonal Antibody
Cat: K109431P
Summary:
| 【Product name】：Anti-API5 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：8539 | 【Swiss Prot】：Q9BZZ5 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:100-300. | |
| 【Immunogen】：A synthetic peptide of human API5 | |
| 【Public Immunogen Range】：450-500/524aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.
Verified picture:
Immunohistochemistry of paraffin-embedded Human cervical cancer with API5 antibody diluted at 1:200