Anti-API5 Polyclonal Antibody - Cy5.5
Cat: K109431P - Cy5.5
Summary:
| 【Product name】：Anti-API5 Polyclonal Antibody - Cy5.5 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：8539 | 【Swiss Prot】：Q9BZZ5 |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human API5 | |
| 【Public Immunogen Range】：450-500/524aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.
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