Anti-TMEM106A Polyclonal Antibody - SAlexa Fluor 750
Cat: K109436P - SAlexa Fluor 750
Summary:
| 【Product name】：Anti-TMEM106A Polyclonal Antibody - SAlexa Fluor 750 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：113277 | 【Swiss Prot】：Q96A25 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-3000. | |
| 【Immunogen】：A synthetic peptide of human TMEM106A | |
| 【Public Immunogen Range】：60-110/262aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Activates macrophages and polarizes them into M1-like macrophages through the activation of the MAPK and NF-kappaB signaling pathway. Upon activation, upregulates the expression of CD80, CD86, CD69 and MHC II on macrophages, and induces the release of pro-inflammatory cytokines such as TNF, IL1B, IL6, CCL2 and nitric oxide. May play a role in inhibition of proliferation and migration.
Verified picture: