Anti-SFXN1 Polyclonal Antibody
Cat: K109476P
Summary:
| 【Product name】：Anti-SFXN1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：94081 | 【Swiss Prot】：Q9H9B4 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human SFXN1 | |
| 【Public Immunogen Range】：1-237aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway (PubMed:30442778). Mitochondrial serine is converted to glycine and formate, which then exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors (PubMed:30442778). Transports both D-serine and L-serine (PubMed:30442778). Also able to transport other amino-acids, such as alanine (PubMed:30442778). May be indirectly involved in the transport of a component required for iron utilization into or out of the mitochondria (By similarity).
Verified picture:
Immunohistochemistry of paraffin-embedded Human liver cancer with SFXN1 antibody diluted at 1:100
Western blot analysis with SFXN1 antibody diluted at 1:2000;Lane: 293T,MCF7,Mouse liver,Mouse brain,Rat liver