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Anti-SFXN1 Polyclonal Antibody - SAlexa Fluor 532
Cat: K109476P - SAlexa Fluor 532
Summary:
【Product name】:Anti-SFXN1 Polyclonal Antibody - SAlexa Fluor 532 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:94081 【Swiss Prot】:Q9H9B4
【Tested applications】:WB,IHC
【Recommended dilution】:WB 1:1000-3000. IHC 1:50-200.
【Immunogen】:Recombinant protein of human SFXN1
【Public Immunogen Range】:1-237aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway (PubMed:30442778). Mitochondrial serine is converted to glycine and formate, which then exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors (PubMed:30442778). Transports both D-serine and L-serine (PubMed:30442778). Also able to transport other amino-acids, such as alanine (PubMed:30442778). May be indirectly involved in the transport of a component required for iron utilization into or out of the mitochondria (By similarity).
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