Anti-AKR1B10 Polyclonal Antibody
Cat: K109534P
Summary:
| 【Product name】：Anti-AKR1B10 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：57016 | 【Swiss Prot】：O60218 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:5000-8000. IHC 1:100-300. | |
| 【Immunogen】：Recombinant protein of human AKR1B10 | |
| 【Public Immunogen Range】：1-317aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols. Displays strong enzymatic activity toward all-trans-retinal, 9-cis-retinal, and 13-cis-retinal. Plays a critical role in detoxifying dietary and lipid-derived unsaturated carbonyls, such as crotonaldehyde, 4-hydroxynonenal, trans-2-hexenal, trans-2,4-hexadienal and their glutathione-conjugates carbonyls (GS-carbonyls). Displays no reductase activity towards glucose.
Verified picture:
Western blot analysis with AKR1B10 antibody diluted at 1:6000;Lane: Raji,293T,A549,Mouse kidney,Rat intestine
Immunohistochemistry of paraffin-embedded Human pancreatic cancer with AKR1B10 antibody diluted at 1:200