Anti-FZD4 Polyclonal Antibody
Cat: K109620P
Summary:
| 【Product name】：Anti-FZD4 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：8322 | 【Swiss Prot】：Q9ULV1 |
| 【Tested applications】：WB,IHC,IF | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. IF 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human FZD4 | |
| 【Public Immunogen Range】：110-160/537aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.
Verified picture:
Western blot analysis with FZD4 antibody diluted at 1:2000;Lane: B16,HepG2,Mouse eye,Mouse trachea
Immunohistochemistry of paraffin-embedded Human stomach cancer with FZD4 antibody diluted at 1:100