Anti-BTK Polyclonal Antibody - SAlexa Fluor 405
Cat: K109662P - SAlexa Fluor 405
Summary:
| 【Product name】：Anti-BTK Polyclonal Antibody - SAlexa Fluor 405 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：695 | 【Swiss Prot】：Q06187 |
| 【Tested applications】：WB,IF,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:100-300. IF 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human BTK | |
| 【Public Immunogen Range】：380-430/659aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
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