Anti-VTA1 Polyclonal Antibody
Cat: K109677P
Summary:
| 【Product name】：Anti-VTA1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：51534 | 【Swiss Prot】：Q9NP79 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:100-300. | |
| 【Immunogen】：Recombinant protein of human VTA1 | |
| 【Public Immunogen Range】：1-308aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR (By similarity). Involved in HIV-1 budding.
Verified picture:
Western blot analysis with VTA1 antibody diluted at 1:2000;Lane:HeLa,SW480,HEK293, K-562,HepG2,HL-60,THP-1
Immunohistochemistry of paraffin-embedded Human colorectal cancer with VTA1 antibody diluted at 1:200
Immunohistochemistry of paraffin-embedded Human pancreatic cancer with VTA1 antibody diluted at 1:200