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Anti-MTCH2 Polyclonal Antibody - SAlexa Fluor 488
Cat: K109703P - SAlexa Fluor 488
Summary:
【Product name】:Anti-MTCH2 Polyclonal Antibody - SAlexa Fluor 488 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Octanoic acid-ammonium sulfate precipitation
【Gene ID】:23788 【Swiss Prot】:Q9Y6C9
【Tested applications】:FC ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human MTCH2
【Public Immunogen Range】:1-304aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
This gene encodes a member of the SLC25 family of nuclear-encoded transporters that are localized in the inner mitochondrial membrane. Members of this superfamily are involved in many metabolic pathways and cell functions. Genome-wide association studies in human have identified single-nucleotide polymorphisms in several loci associated with obesity. This gene is one such locus, which is highly expressed in white adipose tissue and adipocytes, and thought to play a regulatory role in adipocyte differentiation and biology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA can give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon.
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