Anti-FAIM3 Polyclonal Antibody
Cat: K109762P
Summary:
| 【Product name】：Anti-FAIM3 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：9214 | 【Swiss Prot】：O60667 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:100-300. | |
| 【Immunogen】：Recombinant protein of Human FAIM3 | |
| 【Public Immunogen Range】：1-391aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.
Verified picture:
Immunohistochemistry of paraffin-embedded Human colorectal cancer with FAIM3 antibody diluted at 1:200