Anti-SRGAP1 Polyclonal Antibody
Cat: K109783P
Summary:
| 【Product name】：Anti-SRGAP1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：57522 | 【Swiss Prot】：Q7Z6B7 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:100-300. | |
| 【Immunogen】：Recombinant protein of Human SRGAP1 | |
| 【Public Immunogen Range】：1-350aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42.
Verified picture:
Western blot analysis with SRGAP1 antibody diluted at 1:2000;Lane: SHSY5Y
Immunohistochemistry of paraffin-embedded Human liver cancer with SRGAP1 antibody diluted at 1:200
Immunohistochemistry of paraffin-embedded Human testis cancer with SRGAP1 antibody diluted at 1:200