Anti-CABLES1 Polyclonal Antibody
Cat: K109822P
Summary:
| 【Product name】：Anti-CABLES1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：91768 | 【Swiss Prot】：Q8TDN4 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:100-300. | |
| 【Immunogen】：A synthetic peptide of human CABLES1 | |
| 【Public Immunogen Range】：215-265/633aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death (By similarity).
Verified picture:
Western blot analysis with CABLES1 antibody diluted at 1:2000;Lane: HeLa,MCF7,HT29,Mouse brain
Immunohistochemistry of paraffin-embedded Human breast cancer with CABLES1 antibody diluted at 1:200
Immunohistochemistry of paraffin-embedded Mouse brain with CABLES1 antibody diluted at 1:200