Anti-EWSR1 Polyclonal Antibody - RBITC
Cat: K109844P - RBITC
Summary:
| 【Product name】：Anti-EWSR1 Polyclonal Antibody - RBITC | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：2130 | 【Swiss Prot】：Q01844 |
| 【Tested applications】：WB ELISA IHC ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human EWSR1 | |
| 【Public Immunogen Range】：245-295/656aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.
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