Anti-DYRK1B Polyclonal Antibody
Cat: K109855P
Summary:
| 【Product name】：Anti-DYRK1B Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：9149 | 【Swiss Prot】：Q9Y463 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:100-300. | |
| 【Immunogen】：A synthetic peptide of human DYRK1B | |
| 【Public Immunogen Range】：330-380/629aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments. Inhibits the SHH and WNT1 pathways, thereby enhancing adipogenesis. In addition, promotes expression of the gluconeogenic enzyme glucose-6-phosphatase (G6PC).
Verified picture:
Western blot analysis with DYRK1B antibody diluted at 1:2000;Lane: SH-SY5Y,MCF7,Jurkat,C2C12,Mouse testis
Immunohistochemistry of paraffin-embedded Human prostate cancer with DYRK1B antibody diluted at 1:200
Immunohistochemistry of paraffin-embedded Human thyroid cancer with DYRK1B antibody diluted at 1:200