Anti-GRB14 Polyclonal Antibody - RBITC
Cat: K109883P - RBITC
Summary:
| 【Product name】：Anti-GRB14 Polyclonal Antibody - RBITC | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：2888 | 【Swiss Prot】：Q14449 |
| 【Tested applications】：WB ELISA IHC ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide ofHuman GRB14 | |
| 【Public Immunogen Range】：485-535/540aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. This protein likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. This gene may play a role in signaling pathways that regulate growth and metabolism. Alternative splicing results in multiple transcript variants.
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