Anti-RFK Polyclonal Antibody
Cat: K109916P
Summary:
| 【Product name】：Anti-RFK Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：55312 | 【Swiss Prot】：Q969G6 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-3000. | |
| 【Immunogen】：A synthetic peptide ofHuman RFK | |
| 【Public Immunogen Range】：65-115/155aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin-mononucleotide (FMN), hence rate-limiting enzyme in the synthesis of FAD. Essential for TNF-induced reactive oxygen species (ROS) production. Through its interaction with both TNFRSF1A and CYBA, physically and functionally couples TNFRSF1A to NADPH oxidase. TNF-activation of RFK may enhance the incorporation of FAD in NADPH oxidase, a critical step for the assembly and activation of NADPH oxidase.
Verified picture:
Western blot analysis with RFK antibody diluted at 1:2000;Lane:U937,Jurkat,Hela,U87