Anti-NAE1 Polyclonal Antibody
Cat: K109942P
Summary:
| 【Product name】：Anti-NAE1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：8883 | 【Swiss Prot】：Q13564 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:100-300. | |
| 【Immunogen】：A synthetic peptide ofHuman NAE1 | |
| 【Public Immunogen Range】：285-335/534aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Western blot analysis with NAE1 antibody diluted at 1:2000;Lane: HepG2,U251,HEK293,HeLa,293T,PC3,COS7,SHSY5Y,SW480
Immunohistochemistry of paraffin-embedded Human breast cancer with NAE1 antibody diluted at 1:200