Anti-KRT8 Polyclonal Antibody
Cat: K109959P
Summary:
| 【Product name】：Anti-KRT8 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3856 | 【Swiss Prot】：P05787 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:100-300. | |
| 【Immunogen】：A synthetic peptide of human KRT8 | |
| 【Public Immunogen Range】：50-100/483aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.
Verified picture:
Western blot analysis with KRT8 antibody diluted at 1:2000;Lane: MCF7
Immunohistochemistry of paraffin-embedded Human endometrial cancer with KRT8 antibody diluted at 1:200
Immunohistochemistry of paraffin-embedded Human liver cancer with KRT8 antibody diluted at 1:200
Immunohistochemistry of paraffin-embedded Human Lung cancer with KRT8 antibody diluted at 1:200