Anti-NRGN Polyclonal Antibody
Cat: K109992P
Summary:
| 【Product name】：Anti-NRGN Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：4900 | 【Swiss Prot】：Q92686 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:100-300. | |
| 【Immunogen】：A synthetic peptide of human NRGN | |
| 【Public Immunogen Range】：28-78/78aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects.
Verified picture:
Western blot analysis with NRGN antibody diluted at 1:2000;Lane: Rat brain
Immunohistochemistry of paraffin-embedded Mouse brain with NRGN antibody diluted at 1:200
Immunohistochemistry of paraffin-embedded Rat brain with NRGN antibody diluted at 1:200