Anti-SNX17 Polyclonal Antibody
Cat: K110032P
Summary:
| 【Product name】：Anti-SNX17 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：9784 | 【Swiss Prot】：Q15036 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:100-300. | |
| 【Immunogen】：Recombinant protein of Human SNX17 | |
| 【Public Immunogen Range】：1-350aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Critical regulator of endosomal recycling of numerous surface proteins, including integrins, signaling receptor and channels. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Associates with retriever and CCC complexes to prevent lysosomal degradation and promote cell surface recycling of numerous cargos such as integrins ITGB1, ITGB5 and their associated alpha subunits. Also required for maintenance of normal cell surface levels of APP and LRP1. Interacts with membranes containing phosphatidylinositol 3-phosphate.
Verified picture:
Immunohistochemistry of paraffin-embedded Human pancreatic cancer with SNX17 antibody diluted at 1:200
Immunohistochemistry of paraffin-embedded Human stomach cancer with SNX17 antibody diluted at 1:200