Anti-ARHGEF25 Polyclonal Antibody
Cat: K110033P
Summary:
| 【Product name】：Anti-ARHGEF25 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：115557 | 【Swiss Prot】：Q86VW2 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-3000. | |
| 【Immunogen】：Recombinant protein of Human ARHGEF25 | |
| 【Public Immunogen Range】：126-475aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
May play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. It works as a guanine nucleotide exchange factor for Rho family of small GTPases. Links specifically G alpha q/11-coupled receptors to RHOA activation. May be an important regulator of processes involved in axon and dendrite formation. In neurons seems to be an exchange factor primarily for RAC1. Involved in skeletal myogenesis (By similarity).
Verified picture:
Western blot analysis with ARHGEF25 antibody diluted at 1:2000;Lane: Human breast cancer,MCF7,HEK293