Anti-USP21 Polyclonal Antibody - SAlexa Fluor 647
Cat: K110040P - SAlexa Fluor 647
Summary:
| 【Product name】：Anti-USP21 Polyclonal Antibody - SAlexa Fluor 647 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：27005 | 【Swiss Prot】：Q9UK80 |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of Human USP21 | |
| 【Public Immunogen Range】：1-381aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di- and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Regulates gene expression via histone H2A deubiquitination. Also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates. Deubiquitinates BAZ2A/TIP5 leading to its stabilization.
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