Anti-RGS7 Polyclonal Antibody
Cat: K110060P
Summary:
| 【Product name】：Anti-RGS7 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：6000 | 【Swiss Prot】：P49802 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-3000. | |
| 【Immunogen】：Recombinant protein of Human RGS7 | |
| 【Public Immunogen Range】：1-487aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:10521509, PubMed:10862767). The RGS7/GNB5 dimer enhances GNAO1 GTPase activity (PubMed:10521509). May play a role in synaptic vesicle exocytosis (PubMed:12659861). Modulates the activity of potassium channels that are activated by GNAO1 in response to muscarinic acetylcholine receptor M2/CHRM2 signaling (PubMed:15897264).
Verified picture:
Western blot analysis with RGS7 antibody diluted at 1:2000;Lane: Mouse brain,Rat brain