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Anti-ALDH6A1 Polyclonal Antibody
Cat: K110086P
Summary:
【Product name】:Anti-ALDH6A1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:4329 【Swiss Prot】:Q02252
【Tested applications】:WB
【Recommended dilution】:WB 1:8000-12000.
【Immunogen】:Recombinant protein of human ALDH6A1
【Public Immunogen Range】:201-536aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
This gene encodes a member of the aldehyde dehydrogenase protein family. The encoded protein is a mitochondrial methylmalonate semialdehyde dehydrogenase that plays a role in the valine and pyrimidine catabolic pathways. This protein catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. Alternate splicing results in multiple transcript variants.
Verified picture:
Western blot analysis with ALDH6A1 antibody diluted at 1:10000;Lane: Mouse heart, Mouse kidney, Mouse liver,Rat liver,Rat kidney