Anti-DENND1A Polyclonal Antibody
Cat: K110126P
Summary:
| 【Product name】：Anti-DENND1A Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：57706 | 【Swiss Prot】：Q8TEH3 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:100-300. | |
| 【Immunogen】：Recombinant protein of human DENND1A | |
| 【Public Immunogen Range】：1-559aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Guanine nucleotide exchange factor (GEF) regulating clathrin-mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. Regulates clathrin-mediated endocytosis of synaptic vesicles and mediates exit from early endosomes (PubMed:20154091, PubMed:20937701). Binds phosphatidylinositol-phosphates (PtdInsPs), with some preference for PtdIns3P (By similarity).
Verified picture:
Immunohistochemistry of paraffin-embedded Human stomach cancer with DENND1A antibody diluted at 1:200