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Anti-PLEKHF1 Polyclonal Antibody
Cat: K110199P
Summary:
【Product name】:Anti-PLEKHF1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Octanoic acid-ammonium sulfate precipitation
【Gene ID】:79156 【Swiss Prot】:Q96S99
【Tested applications】:IHC
【Recommended dilution】:IHC 1:100-300.
【Immunogen】:A synthetic peptide of human PLEKHF1
【Public Immunogen Range】:215-265/279aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
May induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8
Verified picture:
Immunohistochemistry of paraffin-embedded Human renal cancer with PLEKHF1 antibody diluted at 1:200