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Anti-Phospho-Smad3(S425)Monoclonal Antibody
Cat: K200100M
Summary:
【Product name】:Anti-Phospho-Smad3(S425)Monoclonal Antibody 【Source】:Mouse
【Isotype】:IgG1 【Purification】:Octanoic acid-ammonium sulfate precipitation
【Gene ID】:4088 【Swiss Prot】:P84022
【Tested applications】:IHC
【Recommended dilution】:IHC 1:25-100.
【Immunogen】:Synthetic Peptide
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis. [provided by RefSeq, Apr 2009]
Verified picture:
Immunohistochemistry of paraffin-embedded Human pancreatic cancer Tissue with Phospho-Smad3(S425) antibody diluted at 1:80