Anti-RNF182 Polyclonal Antibody
Cat: K110218P
Summary:
| 【Product name】：Anti-RNF182 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：221687 | 【Swiss Prot】：Q8N6D2 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human RNF182 | |
| 【Public Immunogen Range】：20-70/247aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
E3 ubiquitin-protein ligase that mediates the ubiquitination of ATP6V0C and targets it to degradation via the ubiquitin-proteasome pathway (PubMed:18298843). Plays also a role in the inhibition of TLR-triggered innate immune response by mediating 'Lys'-48-linked ubiquitination and subsequent degradation of NF-kappa-B component RELA (PubMed:31432514).
Verified picture:
Western blot analysis with RNF182 antibody diluted at 1:2000;Lane:Hela,PC-3M-IE8,HepG2
Immunohistochemistry of paraffin-embedded Human colorectal cancer using RNF182 antibody diluted at 1:100